Molecular model of DNA - PCR principle

Objectives: Understand, through manipulation, the mechanisms of faithful DNA replication. Test the conservative, semi-conservative, and dispersive hypotheses of DNA replication, simulate DNA synthesis cycles in vivo and in vitro (PCR).
This new DNA model has a set of neutral ATCG nucleotides (gray); this identification allows for the development of new scenarios.

Replication and Meselson and Stahl experiment:
To replicate this historical experiment, the neutral nucleotides represent the 'heavy' DNA strands. Students can easily test the different hypotheses and quickly visualize the results.

Principle of PCR amplification:
Primer pairs, design and implementation of the initial cycles, impact of the number of cycles, all theoretical aspects of PCR are addressed through manipulation.

Sequencing: this kit is well suited for illustrating different sequencing techniques.

- 240 nucleotides in colors: 60 x A (blue), 60 x T (yellow), 60 x C (green), 60 x G (red)
- 48 neutral nucleotides (gray): 12 x A, 12 x T, 12 x C, 12 x G
- 288 binding tubes